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It's Not Nice to Fool Mother Nature
By Virginia B. Wood
AUGUST 9, 1999:
When Mary Shelley published Frankenstein in 1831, it was arguably the first
techno-thriller, a true science horror story. The novel reflected the British public's
discomfort with the fledgling science of experimental biology. They were horrified
by the dissection of corpses and the vivisection of animals, even though those things
were done in the pursuit of scientific knowledge. The novel's protagonist, Dr. Victor
Frankenstein, ultimately deals with the awful consequences of advancing scientific
discovery when the malevolent result of his experiment wreaks havoc on his life.
For more than 150 years, Mary Shelley's Gothic novel has served as a cautionary
tale about the potential dangers inherent in scientific discovery. Today, British
and European consumers are raising the specter of Frankenstein in their battle against
genetically engineered foods. According to environmental activists worldwide, including
a growing community of environmentally aware American consumers, giant biotechnology
companies are releasing an increasing number of Frankenstein's monsters into the
world food supply. Some irate members of these groups would like to see the new "Frankenfoods"
outlawed completely, while most others agree that a strict policy of labeling foods
which are genetically engineered (GE) should be mandatory.
In response to public outcry, companies such as Monsanto, Novartis, Dow, and DuPont
insist that genetic engineering is really no different from the long-practiced science
of natural selection and crossbreeding. They categorically deny that GE foods offer
any serious health risk to the public and complain that labeling or segregated storage
of GE crops such as corn, soybeans, potatoes, or canola oil used in the preparation
and manufacture of thousands of food items would place an undue financial burden
on producers. When the EU voted to boycott American beef raised on growth hormones,
American companies appealed to the World Trade Organization (WTO) and recently won
a ruling that branded the EU boycott as illegal. However, the battle over GE foods is far from over.
Understanding the Science
The science behind genetic engineering is so complex that even scientists disagree
about the inherent dangers. The information about how any cell functions is encoded
into single and distinct genes, certain segments of DNA with specific instructions
for specific protein production. In front of each gene is a piece of DNA known as
a promoter that regulates the operation of that specific gene. Breeding
is the natural process of cell reproduction between members of the same species,
where genes will always be surrounded by the same DNA unless mutations or accidents
occur. Closely related species might be able to interbreed (a horse and a donkey)
but would almost always produce infertile offspring, a natural safety device that
prevents the mixing of genes. For the purpose of simplification, genetically engineered
foods or genetically modified organisms (GMO) are foods that have had the genes and
pieces of DNA from another species added to their genetic material. This biotechnological
technique makes it possible to break the species barrier, shuffling genes between
totally unrelated species, such as splicing a gene from a North Atlantic flounder
into tomatoes or strawberries to increase their resistance to frost or adding a toxin
lethal to some insect species to corn, cotton, or rape seed.
illustration by Lisa Kirpatrick |
For the spliced genes to work in the new species, they must be introduced with
a promoter that the original species will recognize. In the interest of speed, most
genetic engineering of plants is done with viral promoters because they integrate
their genetic material into the host cell very quickly. The drawback with viral promoters
is that once they're spliced into the host plant, they can't be controlled or switched
off. This can result in unpredictable side effects or pleiotropic effects such as
salmon genetically engineered with a growth hormone gene growing too big too fast
and also turning green, or genes for the color red placed in petunias causing decreased
fertility and altered growth of roots and leaves.
This simplified explanation of genetic engineering technology is based on information
researched and written by Dr. Ricarda Steinbrecher for the Women's Environmental
Trust (WEN), one of Britain's leading environmental charities. Dr. Steinbrecher contributed
a chapter on the science of genetic engineering to Farmageddon: Food and the Culture
of Biotechnology (New Society Publishers, $16.95 paper) by Canadian biotech expert
Brewster Kneen.
Where Are the Regulations?
One of the true mysteries of this situation is how such unpredictable scientific
results have been mainstreamed into the American food supply with almost no long-term
studies to address the many concerns about GE foods. There are three government agencies
responsible for overseeing genetic engineering technologies, and they each have very
specific duties. It is the responsibility of the Food & Drug Administration (FDA)
to determine whether or not GE foods are safe for humans and animals to eat. The
Environmental Protection Agency (EPA) is charged with the responsibility of evaluating
whether altering a crop so that it produces its own pesticide is safe for both the
environment and human consumption. The Department of Agriculture (USDA) checks to
see if the plant grows the way the manufacturer says it will. However, at this point,
it is not within the purview of any U.S. government agency to monitor the long-term
effects of GE foods on people or the ecosystem.
illustration by Lisa Kirpatrick |
In a weekly column called "Focus on the Corporation," Washington journalists
Russell Mokhiber and Robert Weissman reported that some public interest groups have
sued the FDA, alleging the agency "violated federal law by allowing biotech
foods onto the market without first adequately testing the foods for safety"
or labeling them with necessary consumer information. The federal Food, Drug &
Cosmetic Act incorporates the precautionary principle that a new food additive is
presumed unsafe until it is established to be safe through standard scientific procedures.
However, the FDA ruled in 1992 that genetically engineered foods are not new food
additives. According to documents obtained during the discovery process of the lawsuit,
this ruling was made over the objections of some FDA scientists who "warned
that foods produced through recombinant DNA technology entail different risks than
do their conventionally produced counterparts." The giant biotechnology firms
(Monsanto, DuPont, et al) responsible for these products operate on the premise that
genetic engineering is no different from the time-honored conventional selection
and breeding processes, and the FDA seems to accept that explanation over the objections
of many of their own scientific experts.
The danger here appears to be that the FDA (not unlike some other federal agencies)
has long since forsaken its regulatory imperative and traded it in for a promotional
role in speeding new products developed by giant agribusiness concerns onto the market.
The formerly stringent review process necessary for new products has been replaced
by a more congenial approval process. And though they disregard suggestions from
their own scientists, FDA representatives consistently repeat the mantra that all
decisions are based on "sound science." The upshot of this attitude change
is that government agencies designed to regulate business and protect the public
interest seem much more invested in product promotion and protecting the corporate
sector from the public.
International Battlegrounds
United States agriculture and trade officials have been butting heads over the
issue of genetically engineered foods with members of the international community
for several years now. One of the most popular new tools used by U.S. officials to
promote GE foods is the assertion that they are absolutely necessary to feed booming
Third World populations in the new millennium. However, this emotional blackmail
technique seems to have backfired on the FDA and the biotech firms when representatives
of 20 African states published a statement denying that gene technologies are the
answer to hunger in their countries. On the contrary, they stated their belief that
it would "destroy the diversity, the local knowledge and the sustainable agricultural
systems ... and undermine our capacity to feed ourselves." After this statement
became public knowledge, U.S. trade officials pressured European Union (EU) representatives
to bring the African countries into the GE fold with no success.
The trade war erupting over the EU's 10-year ban on importing American beef that
has been treated with growth hormones is another case in point. A majority of the
beef cattle raised in the U.S. are treated with growth hormones, and Europe represents
a large export market, so American officials appealed the ban to the World Trade
Organization (WTO). The WTO has twice ruled the boycott to be illegal, but the EU
refuses to lift the ban, citing the fear shared by many Europeans that there are
possible links between growth hormones and cancer. Therefore, U.S. trade officials
last week levied 100% tariffs on a large list of European gourmet items to
penalize boycott supporters in France, Germany, Denmark, and Italy. English
products escape the stiff tariffs because the English will import U.S. beef.
In response to the EU boycott of American hormone beef, U.S. Secretary of Agriculture
Dan Glickman appeared on ABC's World News Tonight, minimizing the concerns
of European consumers by saying that European producers "simply refuse to modernize
and don't have a reliable system of food regulation in place. They just don't have
the same sophisticated mechanism to scientifically examine their food products and
determine their safety that we do." Most U.S. government and business officials
who are quoted regarding the EU beef boycott describe Europeans in condescending
terms, using words like "hysterical, unsophisticated, or ignorant."
A Reasonable Voice
In the deluge of print and online information about the GE foods issue that have
been generated recently, one of the most intelligent, well-reasoned responses has
come from Charles, Prince of Wales. A lifelong environmentalist, the prince set up
a discussion forum regarding genetically modified organisms on his Web site late
last year to encourage wider public debate on what he considered an important issue
and received more than 10,000 responses. In an op-ed piece written for the London
Daily Mail on June 1, the prince raised several important questions about the
value of genetic engineering technology to the people of Britain at the very same
time Prime Minister Tony Blair's government was attempting to calm the public's fears
about GE crops and foods.
illustration by Lisa Kirpatrick |
The article decries the release of so many GE crops onto the world market before
they were subjected to adequate scientific testing to determine the long-term behavior
of the plants. It also raises legitimate concerns about why rules for the approval
of GE foods are so much less stringent than those for the approval of new medicines
using the same genetic engineering technology. The Prince of Wales points out that
most of the benefits of GE technology accrue to the corporations who invented it
and large corporate farming operations and wonders how hundreds of thousands of acres
of genetically modified corn could be grown in the U.S. before it was known that
the corn pollen would be toxic to monarch butterflies. Was the potential destruction
of monarchs deemed an acceptable risk by the manufacturer of Bt corn, and if so,
how many more negative environmental surprises can we expect from these transgenic
crops?
Regarding the new claims that GE crops are the only way to feed the Third World's
burgeoning population, Prince Charles raises the issue of whether or not there is
any serious research to substantiate that grandiose claim and cites the rejection
of GE technology by the leaders of 20 African countries. He also poses a very worthwhile
question, namely "how much more could be achieved if all the research funds
currently devoted to fashionable GM techniques (billions per year) were applied to
improving methods of agriculture which have stood the test of time?"
In the conclusion to his "thought piece," the prince encourages the
public to consider just what kind of a world they want to inhabit and pass on to
their children, one that allows "the industrialization of life itself, redesigning
the natural world" for the sake of convenience and corporate profit, or a world
that adopts a "more considered approach ... making better, more sustainable
use of what we have, for the long-term benefit of mankind as a whole."
Such an enlightened and reasoned approach to this contentious issue is encouraging:
A respected environmentalist with no profit motive makes a compelling argument against
potential Frankenstein's monsters in our food supply, in contrast to corporate biotech
profiteers promoting science and technology as mankind's only savior. Consumer concerns
about tampering with the balance of nature are legitimate and should be voiced repeatedly
until governments and the businesses they support begin to listen.

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